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Downregulated ESRP1/2 promotes lung metastasis of bladder carcinoma through altering FGFR2 splicing and macrophage polarization

INTRODUCTION: Lung metastasis occurs in parts of the bladder carcinoma (BC) patients but represents the highest severity and a poor outcome of the disease. The molecular mechanism underlying lung metastasis of BC is not fully understood. Fibroblast growth factor receptor 2 (FGFR2) signaling plays a...

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Detalles Bibliográficos
Autores principales: Zhao, Yuyang, Li, Mingyang, Wu, Wenbo, Miao, Wenhao, Liu, Haitao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10113678/
https://www.ncbi.nlm.nih.gov/pubmed/37090731
http://dx.doi.org/10.3389/fimmu.2023.1161273