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Hyperglycemia disturbs trophoblast functions and subsequently leads to failure of uterine spiral artery remodeling

Uterine spiral artery remodeling is necessary for fetal growth and development as well as pregnancy outcomes. During remodeling, trophoblasts invade the arteries, replace the endothelium and disrupt the vascular smooth muscle, and are strictly regulated by the local microenvironment. Elevated glucos...

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Detalles Bibliográficos
Autores principales: Zhu, Yueyue, Liu, Xiaorui, Xu, Yichi, Lin, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10113679/
https://www.ncbi.nlm.nih.gov/pubmed/37091848
http://dx.doi.org/10.3389/fendo.2023.1060253