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HiTAIC: hierarchical tumor artificial intelligence classifier traces tissue of origin and tumor type in primary and metastasized tumors using DNA methylation

Human cancers are heterogenous by their cell composition and origination site. Cancer metastasis generates the conundrum of the unknown origin of migrated tumor cells. Tracing tissue of origin and tumor type in primary and metastasized cancer is vital for clinical significance. DNA methylation alter...

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Detalles Bibliográficos
Autores principales: Zhang, Ze, Lu, Yunrui, Vosoughi, Soroush, Levy, Joshua J, Christensen, Brock C, Salas, Lucas A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10113876/
https://www.ncbi.nlm.nih.gov/pubmed/37089814
http://dx.doi.org/10.1093/narcan/zcad017