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Label-free autofluorescence lifetime reveals the structural dynamics of ataxin-3 inside droplets formed via liquid–liquid phase separation

Liquid–liquid phase separation is a phenomenon that features the formation of liquid droplets containing concentrated solutes. The droplets of neurodegeneration-associated proteins are prone to generate aggregates and cause diseases. To uncover the aggregation process from the droplets, it is necess...

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Detalles Bibliográficos
Autores principales: Matsuura, Uchu, Tahara, Shinya, Kajimoto, Shinji, Nakabayashi, Takakazu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10113985/
https://www.ncbi.nlm.nih.gov/pubmed/37076520
http://dx.doi.org/10.1038/s41598-023-33268-y