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Label-free autofluorescence lifetime reveals the structural dynamics of ataxin-3 inside droplets formed via liquid–liquid phase separation
Liquid–liquid phase separation is a phenomenon that features the formation of liquid droplets containing concentrated solutes. The droplets of neurodegeneration-associated proteins are prone to generate aggregates and cause diseases. To uncover the aggregation process from the droplets, it is necess...
Autores principales: | Matsuura, Uchu, Tahara, Shinya, Kajimoto, Shinji, Nakabayashi, Takakazu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10113985/ https://www.ncbi.nlm.nih.gov/pubmed/37076520 http://dx.doi.org/10.1038/s41598-023-33268-y |
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