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A tool for nuclear imaging of the SARS-CoV-2 entry receptor: molecular model and preclinical development of ACE2-selective radiopeptides

PURPOSE: The angiotensin converting enzyme-2 (ACE2)—entry receptor of SARS-CoV-2—and its homologue, the angiotensin-converting enzyme (ACE), play a pivotal role in maintaining cardiovascular homeostasis. Potential changes in ACE2 expression levels and dynamics after SARS-CoV-2 infection have been ba...

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Detalles Bibliográficos
Autores principales: Beyer, Darja, Vaccarin, Christian, Deupi, Xavier, Mapanao, Ana Katrina, Cohrs, Susan, Sozzi-Guo, Fan, Grundler, Pascal V., van der Meulen, Nicholas P., Wang, Jinling, Tanriver, Matthias, Bode, Jeffrey W., Schibli, Roger, Müller, Cristina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10113987/
https://www.ncbi.nlm.nih.gov/pubmed/37074529
http://dx.doi.org/10.1186/s13550-023-00979-2