Single-cell transcriptional and functional analysis of dopaminergic neurons in organoid-like cultures derived from human fetal midbrain

Significant efforts are ongoing to develop refined differentiation protocols to generate midbrain dopamine (DA) neurons from pluripotent stem cells for application in disease modeling, diagnostics, drug screening and cell-based therapies for Parkinson's disease. An increased understanding of th...

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Detalles Bibliográficos
Autores principales: Birtele, Marcella, Storm, Petter, Sharma, Yogita, Kajtez, Janko, Wahlestedt, Jenny Nelander, Sozzi, Edoardo, Nilsson, Fredrik, Stott, Simon, He, Xiaoling L., Mattsson, Bengt, Ottosson, Daniella Rylander, Barker, Roger A., Fiorenzano, Alessandro, Parmar, Malin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2022
Materias:
Human Development
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10114107/
https://www.ncbi.nlm.nih.gov/pubmed/36305490
http://dx.doi.org/10.1242/dev.200504

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10114107/
https://www.ncbi.nlm.nih.gov/pubmed/36305490
http://dx.doi.org/10.1242/dev.200504

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