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Integrative analysis of TP53 mutations in lung adenocarcinoma for immunotherapies and prognosis

BACKGROUND: The TP53 tumor suppressor gene is one of the most mutated genes in lung adenocarcinoma (LUAD) and plays a vital role in regulating the occurrence and progression of cancer. We aimed to elucidate the association between TP53 mutations, response to immunotherapies and the prognosis of LUAD...

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Detalles Bibliográficos
Autores principales: Li, He, Yang, Lei, Wang, Yuanyuan, Wang, Lingchan, Chen, Gang, Zhang, Li, Wang, Dongchang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10114340/
https://www.ncbi.nlm.nih.gov/pubmed/37072703
http://dx.doi.org/10.1186/s12859-023-05268-2