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Central nervous system insulin signaling can influence the rate of insulin influx into brain

BACKGROUND: Insulin transport across the blood-brain barrier (BBB) is a highly regulated, saturable process, known to be affected by many peripheral substrates including insulin itself and triglycerides. This is in contrast to insulin leakage into peripheral tissues. Whether the central nervous syst...

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Detalles Bibliográficos
Autores principales: Nguyen, Van, Thomas, Peter, Pemberton, Sarah, Babin, Alice, Noonan, Cassidy, Weaver, Riley, Banks, William A., Rhea, Elizabeth M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10114367/
https://www.ncbi.nlm.nih.gov/pubmed/37076875
http://dx.doi.org/10.1186/s12987-023-00431-6