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Serum metabolomics profiling by proton nuclear magnetic resonance spectroscopy reveals sexual dimorphism and masculinization of intermediate metabolism in women with polycystic ovary syndrome (PCOS)

BACKGROUND: The polycystic ovary syndrome (PCOS) is associated with insulin resistance, obesity and cardiometabolic comorbidities. We here challenged the hypothesis, using state-of-the art proton nuclear magnetic resonance spectroscopy metabolomics profiling, that androgen excess in women induces al...

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Detalles Bibliográficos
Autores principales: Escobar-Morreale, Héctor F., Martínez-García, M. Ángeles, Insenser, María, Cañellas, Nicolau, Correig, Xavier, Luque-Ramírez, Manuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10114375/
https://www.ncbi.nlm.nih.gov/pubmed/37076926
http://dx.doi.org/10.1186/s13293-023-00507-w