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PAR2 activation in the dura causes acute behavioral responses and priming to glyceryl trinitrate in a mouse migraine model

BACKGROUND: Migraine is a severely debilitating disorder that affects millions of people worldwide. Studies have indicated that activation of protease-activated receptor-2 (PAR2) in the dura mater causes headache responses in preclinical models. It is also well known that vasodilators such as nitric...

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Detalles Bibliográficos
Autores principales: Mason, Bianca N., Hassler, Shayne N., DeFea, Kathryn, Boitano, Scott, Vagner, Josef, Price, Theodore J., Dussor, Greg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Milan 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10114383/
https://www.ncbi.nlm.nih.gov/pubmed/37072694
http://dx.doi.org/10.1186/s10194-023-01574-5