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PAR2 activation in the dura causes acute behavioral responses and priming to glyceryl trinitrate in a mouse migraine model
BACKGROUND: Migraine is a severely debilitating disorder that affects millions of people worldwide. Studies have indicated that activation of protease-activated receptor-2 (PAR2) in the dura mater causes headache responses in preclinical models. It is also well known that vasodilators such as nitric...
Autores principales: | Mason, Bianca N., Hassler, Shayne N., DeFea, Kathryn, Boitano, Scott, Vagner, Josef, Price, Theodore J., Dussor, Greg |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Milan
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10114383/ https://www.ncbi.nlm.nih.gov/pubmed/37072694 http://dx.doi.org/10.1186/s10194-023-01574-5 |
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