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Urate-lowering therapy following a treat-to-target continuation strategy compared to a treat-to-avoid-symptoms discontinuation strategy in gout patients in remission (GO TEST Finale): study protocol of a multicentre pragmatic randomized superiority trial

BACKGROUND: Long-term gout treatment is based on reducing serum urate levels using urate-lowering therapy (ULT). Most guidelines recommend using a lifelong continuation treat-to-target (T2T) strategy, in which ULT is dosed or combined until a serum urate target has been reached and maintained. Howev...

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Detalles Bibliográficos
Autores principales: Peeters, Iris Rose, den Broeder, Alfons A., Taylor, William J, den Broeder, Nathan, Flendrie, Marcel, van Herwaarden, Noortje
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10114395/
https://www.ncbi.nlm.nih.gov/pubmed/37072799
http://dx.doi.org/10.1186/s13063-023-07242-y