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Colorectal cancer-derived small extracellular vesicles induce TGFβ1-mediated epithelial to mesenchymal transition of hepatocytes

BACKGROUND: Metastatic disease is the major cause of cancer-related deaths. Increasing evidence shows that primary tumor cells can promote metastasis by preparing the local microenvironment of distant organs, inducing the formation of the so-called “pre-metastatic niche”. In recent years, several st...

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Detalles Bibliográficos
Autores principales: Pucci, Marzia, Moschetti, Marta, Urzì, Ornella, Loria, Marco, Conigliaro, Alice, Di Bella, Maria Antonietta, Crescitelli, Rossella, Olofsson Bagge, Roger, Gallo, Alessia, Santos, Mark F., Puglisi, Caterina, Forte, Stefano, Lorico, Aurelio, Alessandro, Riccardo, Fontana, Simona
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10114452/
https://www.ncbi.nlm.nih.gov/pubmed/37072829
http://dx.doi.org/10.1186/s12935-023-02916-8