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Indoleacrylic acid produced by Parabacteroides distasonis alleviates type 2 diabetes via activation of AhR to repair intestinal barrier

BACKGROUND: Anti-inflammatory therapy is an effective strategy in the treatment of type 2 diabetes (T2D). Studies found that inflammatory responses in vivo were strongly associated with defects in the mucosal barrier function of the gut epithelium. While some microbial strains could help repair the...

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Detalles Bibliográficos
Autores principales: Liu, Deliang, Zhang, Shaobao, Li, Siju, Zhang, Qian, Cai, Ying, Li, Pei, Li, Hao, Shen, Baochun, Liao, Qiongfeng, Hong, Yanjun, Xie, Zhiyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10114473/
https://www.ncbi.nlm.nih.gov/pubmed/37072819
http://dx.doi.org/10.1186/s12915-023-01578-2