A robust reprogramming strategy for generating hepatocyte-like cells usable in pharmaco-toxicological studies

BACKGROUND: High-throughput pharmaco-toxicological testing frequently relies on the use of established liver-derived cell lines, such as HepG2 cells. However, these cells often display limited hepatic phenotype and features of neoplastic transformation that may bias the interpretation of the results...

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Detalles Bibliográficos
Autores principales: Garcia-Llorens, Guillem, Martínez-Sena, Teresa, Pareja, Eugenia, Tolosa, Laia, Castell, José V., Bort, Roque
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10114490/
https://www.ncbi.nlm.nih.gov/pubmed/37072803
http://dx.doi.org/10.1186/s13287-023-03311-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10114490/
https://www.ncbi.nlm.nih.gov/pubmed/37072803
http://dx.doi.org/10.1186/s13287-023-03311-w

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