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A robust reprogramming strategy for generating hepatocyte-like cells usable in pharmaco-toxicological studies
BACKGROUND: High-throughput pharmaco-toxicological testing frequently relies on the use of established liver-derived cell lines, such as HepG2 cells. However, these cells often display limited hepatic phenotype and features of neoplastic transformation that may bias the interpretation of the results...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10114490/ https://www.ncbi.nlm.nih.gov/pubmed/37072803 http://dx.doi.org/10.1186/s13287-023-03311-w |