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Lysyl oxidase-like 4 exerts an atypical role in breast cancer progression that is dependent on the enzymatic activity that targets the cell-surface annexin A2

BACKGROUND: LOX family members are reported to play pivotal roles in cancer. Unlike their enzymatic activities in collagen cross-linking, their precise cancer functions are unclear. We revealed that LOXL4 is highly upregulated in breast cancer cells, and we thus sought to define an unidentified role...

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Detalles Bibliográficos
Autores principales: Komalasari, Ni Luh Gede Yoni, Tomonobu, Nahoko, Kinoshita, Rie, Chen, Youyi, Sakaguchi, Yoshihiko, Gohara, Yuma, Jiang, Fan, Yamamoto, Ken-ich, Murata, Hitoshi, Ruma, I Made Winarsa, Sumardika, I Wayan, Zhou, Jin, Yamauchi, Akira, Kuribayashi, Futoshi, Inoue, Yusuke, Toyooka, Shinichi, Sakaguchi, Masakiyo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10114587/
https://www.ncbi.nlm.nih.gov/pubmed/37091157
http://dx.doi.org/10.3389/fonc.2023.1142907