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Cell-Penetrating d-Peptides Retain Antisense Morpholino Oligomer Delivery Activity

[Image: see text] Cell-penetrating peptides (CPPs) can cross the cell membrane to enter the cytosol and deliver otherwise nonpenetrant macromolecules such as proteins and oligonucleotides. For example, recent clinical trials have shown that a CPP attached to phosphorodiamidate morpholino oligomers (...

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Detalles Bibliográficos
Autores principales: Schissel, Carly K., Farquhar, Charlotte E., Malmberg, Annika B., Loas, Andrei, Pentelute, Bradley L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10114648/
https://www.ncbi.nlm.nih.gov/pubmed/37101743
http://dx.doi.org/10.1021/acsbiomedchemau.1c00053