Continuous Flow Synthesis of A2E Guided by Design of Experiments and High-Throughput Studies

[Image: see text] N-Retinylidene-N-retinylethanolamine (A2E) is the most studied lipid bisretinoid. It forms lipofuscin deposits in the retinal pigment epithelium (RPE), causing vision impairment and blindness in eye conditions, such as Stargardt’s disease, cone-rod dystrophy, Best’s macular dystrop...

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Detalles Bibliográficos
Autores principales: Murbach-Oliveira, Giulia, Banerjee, Kalpita, Nociari, Marcelo M., Thompson, David H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10114832/
https://www.ncbi.nlm.nih.gov/pubmed/37101569
http://dx.doi.org/10.1021/acsbiomedchemau.1c00060

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10114832/
https://www.ncbi.nlm.nih.gov/pubmed/37101569
http://dx.doi.org/10.1021/acsbiomedchemau.1c00060

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