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Adaptive c-Met-PLXDC2 Signaling Axis Mediates Cancer Stem Cell Plasticity to Confer Radioresistance-associated Aggressiveness in Head and Neck Cancer

Radiotherapy plays an essential role in the treatment of head and neck squamous cell carcinoma (HNSCC), yet radioresistance remains a major barrier to therapeutic efficacy. A better understanding of the predominant pathways determining radiotherapy response could help develop mechanism-informed ther...

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Detalles Bibliográficos
Autores principales: Lang, Liwei, Chen, Fanghui, Li, Yamin, Shay, Chloe, Yang, Fan, Dan, Hancai, Chen, Zhuo G., Saba, Nabil F., Teng, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10114932/
https://www.ncbi.nlm.nih.gov/pubmed/37089864
http://dx.doi.org/10.1158/2767-9764.CRC-22-0289