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Identifying developability risks for clinical progression of antibodies using high-throughput in vitro and in silico approaches
With the growing significance of antibodies as a therapeutic class, identifying developability risks early during development is of paramount importance. Several high-throughput in vitro assays and in silico approaches have been proposed to de-risk antibodies during early stages of the discovery pro...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Taylor & Francis
2023
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10114995/ https://www.ncbi.nlm.nih.gov/pubmed/37072706 http://dx.doi.org/10.1080/19420862.2023.2200540 |