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Phospho-tau with subthreshold tau-PET predicts increased tau accumulation rates in amyloid-positive individuals

Different tau biomarkers become abnormal at different stages of Alzheimer’s disease, with CSF phospho-tau typically becoming elevated at subthreshold levels of tau-PET binding. To capitalize on the temporal order of tau biomarker-abnormality and capture the earliest changes of tau accumulation, we i...

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Detalles Bibliográficos
Autores principales: Groot, Colin, Smith, Ruben, Stomrud, Erik, Binette, Alexa Pichet, Leuzy, Antoine, Wuestefeld, Anika, Wisse, Laura E M, Palmqvist, Sebastian, Mattsson-Carlgren, Niklas, Janelidze, Shorena, Strandberg, Olof, Ossenkoppele, Rik, Hansson, Oskar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10115173/
https://www.ncbi.nlm.nih.gov/pubmed/36084009
http://dx.doi.org/10.1093/brain/awac329