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Phospho-tau with subthreshold tau-PET predicts increased tau accumulation rates in amyloid-positive individuals
Different tau biomarkers become abnormal at different stages of Alzheimer’s disease, with CSF phospho-tau typically becoming elevated at subthreshold levels of tau-PET binding. To capitalize on the temporal order of tau biomarker-abnormality and capture the earliest changes of tau accumulation, we i...
Autores principales: | Groot, Colin, Smith, Ruben, Stomrud, Erik, Binette, Alexa Pichet, Leuzy, Antoine, Wuestefeld, Anika, Wisse, Laura E M, Palmqvist, Sebastian, Mattsson-Carlgren, Niklas, Janelidze, Shorena, Strandberg, Olof, Ossenkoppele, Rik, Hansson, Oskar |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10115173/ https://www.ncbi.nlm.nih.gov/pubmed/36084009 http://dx.doi.org/10.1093/brain/awac329 |
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