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Measures of cortical microstructure are linked to amyloid pathology in Alzheimer’s disease

Markers of downstream events are a key component of clinical trials of disease-modifying therapies for Alzheimer’s disease. Morphological metrics like cortical thickness are established measures of atrophy but are not sensitive enough to detect amyloid-beta (Aβ)- related changes that occur before ov...

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Detalles Bibliográficos
Autores principales: Spotorno, Nicola, Strandberg, Olof, Vis, Geraline, Stomrud, Erik, Nilsson, Markus, Hansson, Oskar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10115177/
https://www.ncbi.nlm.nih.gov/pubmed/36130332
http://dx.doi.org/10.1093/brain/awac343