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Temporal lobe epilepsy with GAD antibodies: neurons killed by T cells not by complement membrane attack complex

Temporal lobe epilepsy (TLE) is one of the syndromes linked to antibodies against glutamic acid decarboxylase (GAD). It has been questioned whether ‘limbic encephalitis with GAD antibodies’ is a meaningful diagnostic entity. The immunopathogenesis of GAD-TLE has remained enigmatic. Improvement of im...

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Detalles Bibliográficos
Autores principales: Tröscher, Anna R, Mair, Katharina M, Verdú de Juan, Laia, Köck, Ulrike, Steinmaurer, Anja, Baier, Hartmut, Becker, Albert, Blümcke, Ingmar, Finzel, Martin, Geis, Christian, Höftberger, Romana, Mawrin, Christian, von Oertzen, Tim J, Pitsch, Julika, Surges, Rainer, Voges, Berthold, Weis, Serge, Winklehner, Michael, Woermann, Friedrich, Bauer, Jan, Bien, Christian G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10115353/
https://www.ncbi.nlm.nih.gov/pubmed/36314080
http://dx.doi.org/10.1093/brain/awac404