Vaccination of SARS-CoV-2-infected individuals expands a broad range of clonally diverse affinity-matured B cell lineages

Vaccination of SARS-CoV-2 convalescent individuals generates broad and potent antibody responses. Here, we isolate 459 spike-specific monoclonal antibodies (mAbs) from two individuals who were infected with the index variant of SARS-CoV-2 and later boosted with mRNA-1273. We characterize mAb genetic...

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Detalles Bibliográficos
Autores principales: Chernyshev, Mark, Sakharkar, Mrunal, Connor, Ruth I., Dugan, Haley L., Sheward, Daniel J., Rappazzo, C. G., Stålmarck, Aron, Forsell, Mattias N. E., Wright, Peter F., Corcoran, Martin, Murrell, Ben, Walker, Laura M., Karlsson Hedestam, Gunilla B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10115384/
https://www.ncbi.nlm.nih.gov/pubmed/37076511
http://dx.doi.org/10.1038/s41467-023-37972-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10115384/
https://www.ncbi.nlm.nih.gov/pubmed/37076511
http://dx.doi.org/10.1038/s41467-023-37972-1

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