Autophagy supports mitochondrial metabolism through the regulation of iron homeostasis in pancreatic cancer

Pancreatic ductal adenocarcinoma (PDAC) cells maintain a high level of autophagy, allowing them to thrive in an austere microenvironment. However, the processes through which autophagy promotes PDAC growth and survival are still not fully understood. Here, we show that autophagy inhibition in PDAC a...

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Detalles Bibliográficos
Autores principales: Mukhopadhyay, Subhadip, Encarnación-Rosado, Joel, Lin, Elaine Y., Sohn, Albert S. W., Zhang, Huan, Mancias, Joseph D., Kimmelman, Alec C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2023
Materias:
Biomedicine and Life Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10115412/
https://www.ncbi.nlm.nih.gov/pubmed/37075122
http://dx.doi.org/10.1126/sciadv.adf9284

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10115412/
https://www.ncbi.nlm.nih.gov/pubmed/37075122
http://dx.doi.org/10.1126/sciadv.adf9284

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