An SPNS1-dependent lysosomal lipid transport pathway that enables cell survival under choline limitation

Lysosomes degrade macromolecules and recycle their nutrient content to support cell function and survival. However, the machineries involved in lysosomal recycling of many nutrients remain to be discovered, with a notable example being choline, an essential metabolite liberated via lipid degradation...

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Detalles Bibliográficos
Autores principales: Scharenberg, Samantha G., Dong, Wentao, Ghoochani, Ali, Nyame, Kwamina, Levin-Konigsberg, Roni, Krishnan, Aswini R., Rawat, Eshaan S., Spees, Kaitlyn, Bassik, Michael C., Abu-Remaileh, Monther
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2023
Materias:
Biomedicine and Life Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10115416/
https://www.ncbi.nlm.nih.gov/pubmed/37075117
http://dx.doi.org/10.1126/sciadv.adf8966

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10115416/
https://www.ncbi.nlm.nih.gov/pubmed/37075117
http://dx.doi.org/10.1126/sciadv.adf8966

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