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AGS3 antagonizes LGN to balance oriented cell divisions and cell fate choices in mammalian epidermis

Oriented cell divisions balance self-renewal and differentiation in stratified epithelia such as the skin epidermis. During peak epidermal stratification, the distribution of division angles among basal keratinocyte progenitors is bimodal, with planar and perpendicular divisions driving symmetric an...

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Detalles Bibliográficos
Autores principales: Descovich, Carlos P, Lough, Kendall J, Jena, Akankshya, Wu, Jessica J, Yom, Jina, Spitzer, Danielle C, Uppalapati, Manuela, Kedziora, Katarzyna M, Williams, Scott E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10115442/
https://www.ncbi.nlm.nih.gov/pubmed/37017303
http://dx.doi.org/10.7554/eLife.80403