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Parahydrogen-induced polarization allows 2000-fold signal enhancement in biologically active derivatives of the peptide-based drug octreotide

Octreotide, a somatostatin analogue, has shown its efficacy for the diagnostics and treatment of various types of cancer, i.e., in octreotide scan, as radio-marker after labelling with a radiopharmaceutical. To avoid toxicity of radio-labeling, octreotide-based assays can be implemented into magneti...

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Detalles Bibliográficos
Autores principales: Lins, Jonas, Miloslavina, Yuliya A., Carrara, Stefania C., Rösler, Lorenz, Hofmann, Sarah, Herr, Kevin, Theiß, Franziska, Wienands, Laura, Avrutina, Olga, Kolmar, Harald, Buntkowsky, Gerd
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10115808/
https://www.ncbi.nlm.nih.gov/pubmed/37076553
http://dx.doi.org/10.1038/s41598-023-33577-2