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Loss of Dead end1 induces testicular teratomas from primordial germ cells that failed to undergo sexual differentiation in embryonic testes

Spontaneous testicular teratomas (STTs) are tumours comprising a diverse array of cell and tissue types, which are derived from pluripotent stem-like cells called embryonal carcinoma cells (ECCs). Although mouse ECCs originate from primordial germ cells (PGCs) in embryonic testes, the molecular basi...

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Detalles Bibliográficos
Autores principales: Imai, Atsuki, Matsuda, Kazuya, Niimi, Yuki, Suzuki, Atsushi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10115811/
https://www.ncbi.nlm.nih.gov/pubmed/37076592
http://dx.doi.org/10.1038/s41598-023-33706-x