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Dephosphocholination by Legionella effector Lem3 functions through remodelling of the switch II region of Rab1b

Bacterial pathogens often make use of post-translational modifications to manipulate host cells. Legionella pneumophila, the causative agent of Legionnaires disease, secretes the enzyme AnkX that uses cytidine diphosphate-choline to post-translationally modify the human small G-Protein Rab1 with a p...

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Detalles Bibliográficos
Autores principales: Kaspers, Marietta S., Pogenberg, Vivian, Pett, Christian, Ernst, Stefan, Ecker, Felix, Ochtrop, Philipp, Groll, Michael, Hedberg, Christian, Itzen, Aymelt
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10115812/
https://www.ncbi.nlm.nih.gov/pubmed/37076474
http://dx.doi.org/10.1038/s41467-023-37621-7