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One to one comparison of cell-free synthesized erythropoietin conjugates modified with linear polyglycerol and polyethylene glycol

With more than 20 Food and Drug Administration (FDA)-approved poly (ethylene glycol) (PEG) modified drugs on the market, PEG is the gold standard polymer in bioconjugation. The coupling improves stability, efficiency and can prolong blood circulation time of therapeutic proteins. Even though PEGylat...

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Detalles Bibliográficos
Autores principales: Pouyan, Paria, Zemella, Anne, Schloßhauer, Jeffrey L., Walter, Ruben M., Haag, Rainer, Kubick, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10115831/
https://www.ncbi.nlm.nih.gov/pubmed/37076514
http://dx.doi.org/10.1038/s41598-023-33463-x