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Exploiting convergent phenotypes to derive a pan-cancer cisplatin response gene expression signature

Precision medicine offers remarkable potential for the treatment of cancer, but is largely focused on tumors that harbor actionable mutations. Gene expression signatures can expand the scope of precision medicine by predicting response to traditional (cytotoxic) chemotherapy agents without relying o...

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Detalles Bibliográficos
Autores principales: Scarborough, Jessica A., Eschrich, Steven A., Torres-Roca, Javier, Dhawan, Andrew, Scott, Jacob G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10115855/
https://www.ncbi.nlm.nih.gov/pubmed/37076665
http://dx.doi.org/10.1038/s41698-023-00375-y