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Multi-omic underpinnings of epigenetic aging and human longevity

Biological aging is accompanied by increasing morbidity, mortality, and healthcare costs; however, its molecular mechanisms are poorly understood. Here, we use multi-omic methods to integrate genomic, transcriptomic, and metabolomic data and identify biological associations with four measures of epi...

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Detalles Bibliográficos
Autores principales: Mavromatis, Lucas A., Rosoff, Daniel B., Bell, Andrew S., Jung, Jeesun, Wagner, Josephin, Lohoff, Falk W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10115892/
https://www.ncbi.nlm.nih.gov/pubmed/37076473
http://dx.doi.org/10.1038/s41467-023-37729-w