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Severe COVID-19 and non-COVID-19 severe sepsis converge transcriptionally after a week in the intensive care unit, indicating common disease mechanisms

INTRODUCTION: Severe COVID-19 and non-COVID-19 pulmonary sepsis share pathophysiological, immunological, and clinical features. To what extent they share mechanistically-based gene expression trajectories throughout hospitalization was unknown. Our objective was to compare gene expression trajectori...

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Detalles Bibliográficos
Autores principales: An, Andy Y., Baghela, Arjun, Zhang, Peter, Falsafi, Reza, Lee, Amy H., Trahtemberg, Uriel, Baker, Andrew J., dos Santos, Claudia C., Hancock, Robert E. W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10115984/
https://www.ncbi.nlm.nih.gov/pubmed/37090709
http://dx.doi.org/10.3389/fimmu.2023.1167917