Gut microbiota from sigma-1 receptor knockout mice induces depression-like behaviors and modulates the cAMP/CREB/BDNF signaling pathway

INTRODUCTION: Depression is a common mental disorder that affects approximately 350 million people worldwide. Much remains unknown about the molecular mechanisms underlying this complex disorder. Sigma-1 receptor (Sig-1R) is expressed at high levels in the central nervous system. Increasing evidence...

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Detalles Bibliográficos
Autores principales: Li, Jia-Hao, Liu, Jia-Li, Li, Xiu-Wen, Liu, Yi, Yang, Jian-Zheng, Chen, Li-Jian, Zhang, Kai-Kai, Xie, Xiao-Li, Wang, Qi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10116000/
https://www.ncbi.nlm.nih.gov/pubmed/37089558
http://dx.doi.org/10.3389/fmicb.2023.1143648

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10116000/
https://www.ncbi.nlm.nih.gov/pubmed/37089558
http://dx.doi.org/10.3389/fmicb.2023.1143648

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