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Morphology engineering for novel antibiotics: Effect of glass microparticles and soy lecithin on rebeccamycin production and cellular morphology of filamentous actinomycete Lentzea aerocolonigenes

Lentzea aerocolonigenes, as an actinomycete, is a natural producer of the antibiotic and antitumoral drug rebeccamycin. Due to the filamentous cellular morphology handling in cultivations is challenging; therefore, morphology engineering techniques are mandatory to enhance productivity. One promisin...

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Detalles Bibliográficos
Autores principales: Dinius, Anna, Schrinner, Kathrin, Schrader, Marcel, Kozanecka, Zuzanna Justyna, Brauns, Henry, Klose, Leon, Weiß, Hannah, Kwade, Arno, Krull, Rainer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10116066/
https://www.ncbi.nlm.nih.gov/pubmed/37091334
http://dx.doi.org/10.3389/fbioe.2023.1171055