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Morphology engineering for novel antibiotics: Effect of glass microparticles and soy lecithin on rebeccamycin production and cellular morphology of filamentous actinomycete Lentzea aerocolonigenes
Lentzea aerocolonigenes, as an actinomycete, is a natural producer of the antibiotic and antitumoral drug rebeccamycin. Due to the filamentous cellular morphology handling in cultivations is challenging; therefore, morphology engineering techniques are mandatory to enhance productivity. One promisin...
Autores principales: | Dinius, Anna, Schrinner, Kathrin, Schrader, Marcel, Kozanecka, Zuzanna Justyna, Brauns, Henry, Klose, Leon, Weiß, Hannah, Kwade, Arno, Krull, Rainer |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10116066/ https://www.ncbi.nlm.nih.gov/pubmed/37091334 http://dx.doi.org/10.3389/fbioe.2023.1171055 |
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