Relationship of Muscle Apolipoprotein E Expression with Markers of Cellular Stress, Metabolism, and Blood Biomarkers in Cognitively Healthy and Impaired Older Adults

BACKGROUND: Individuals with mild cognitive impairment (MCI) have reduced lipid-stimulated mitochondrial respiration in skeletal muscle. A major risk factor for Alzheimer’s disease (AD), the apolipoprotein E4 (APOE4) allele, is implicated in lipid metabolism and is associated with metabolic and oxid...

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Detalles Bibliográficos
Autores principales: Johnson, Chelsea N., McCoin, Colin S., Kueck, Paul J., Hawley, Amelia G., John, Casey S., Thyfault, John P., Swerdlow, Russell H., Geiger, Paige C., Morris, Jill K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10116140/
https://www.ncbi.nlm.nih.gov/pubmed/36847010
http://dx.doi.org/10.3233/JAD-221192

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10116140/
https://www.ncbi.nlm.nih.gov/pubmed/36847010
http://dx.doi.org/10.3233/JAD-221192

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