Beneficial effects of brief early life angiotensin-converting enzyme inhibition wane with time in sheep with solitary functioning kidney

A child with a congenital solitary functioning kidney (SFK) may develop kidney disease from early in life due to hyperfiltration injury. Previously, we showed in a sheep model of SFK that brief angiotensin-converting enzyme inhibition (ACEi) early in life is reno-protective and increases renal funct...

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Detalles Bibliográficos
Autores principales: McArdle, Zoe, Singh, Reetu R., Bielefeldt-Ohmann, Helle, Moritz, Karen M., Denton, Kate M., Schreuder, Michiel F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2023
Materias:
Cardiovascular System & Vascular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10116343/
https://www.ncbi.nlm.nih.gov/pubmed/37018071
http://dx.doi.org/10.1042/CS20220811

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10116343/
https://www.ncbi.nlm.nih.gov/pubmed/37018071
http://dx.doi.org/10.1042/CS20220811

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