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Computational design and molecular modeling of morphine derivatives for preferential binding in inflamed tissue
The opioid epidemic has impacted over 10 million Americans in 2019. Opioids, like morphine, bind non‐selectively in both peripheral tissue, leading to effective pain relief, and central tissue, resulting in dangerous side effects and addiction. The inflamed conditions of injured tissues have a lower...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10116396/ https://www.ncbi.nlm.nih.gov/pubmed/37078224 http://dx.doi.org/10.1002/prp2.1075 |