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Microwave-Assisted Synthesis, Structure, and Preliminary Biological Evaluation of Novel 6-Methoxy-5,6-dihydro-5-azapurines

[Image: see text] We herein disclose the microwave-assisted synthesis of previously unreported 6-methoxy-5,6-dihydro-5-azapurines, whose purine-like scaffold is promising for drug discovery. The method is simple, fast, and relies on easily accessible reagents such as trimethyl orthoformate, acetic a...

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Detalles Bibliográficos
Autores principales: Siutkina, Alena I., Kalinina, Svetlana, Liu, Rongfang, Heitman, Laura H., Junker, Anna, Daniliuc, Constantin G., Kalinin, Dmitrii V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10116508/
https://www.ncbi.nlm.nih.gov/pubmed/37091407
http://dx.doi.org/10.1021/acsomega.3c00765