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Galectin-3 expression in donor T cells reduces GvHD severity and lethality after allogeneic hematopoietic cell transplantation

Abundant donor cytotoxic T cells that attack normal host organs remain a major problem for patients receiving allogeneic hematopoietic cell transplantation (allo-HCT). Despite an increase in our knowledge of the pathobiology of acute graft versus host disease (aGvHD), the mechanisms regulating the p...

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Detalles Bibliográficos
Autores principales: Mohammadpour, Hemn, Tsuji, Takemasa, MacDonald, Cameron R., Sarow, Joseph L., Rosenheck, Hanna, Daneshmandi, Saeed, Choi, Jee Eun, Qiu, Jingxin, Matsuzaki, Junko, Witkiewicz, Agnieszka K., Attwood, Kristopher, Blazar, Bruce R., Odunsi, Kunle, Repasky, Elizabeth A., McCarthy, Philip L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10116561/
https://www.ncbi.nlm.nih.gov/pubmed/36924493
http://dx.doi.org/10.1016/j.celrep.2023.112250