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Ovulatory signal-triggered chromatin remodeling in ovarian granulosa cells by HDAC2 phosphorylation activation-mediated histone deacetylation

BACKGROUND: Epigenetic reprogramming is involved in luteinizing hormone (LH)-induced ovulation; however, the underlying mechanisms are largely unknown. RESULTS: We here observed a rapid histone deacetylation process between two waves of active transcription mediated by the follicle-stimulating hormo...

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Detalles Bibliográficos
Autores principales: Jin, Jiamin, Ren, Peipei, Li, Xiang, Zhang, Yinyi, Yang, Weijie, Ma, Yerong, Lai, Mengru, Yu, Chao, Zhang, Songying, Zhang, Yin-Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10116676/
https://www.ncbi.nlm.nih.gov/pubmed/37076890
http://dx.doi.org/10.1186/s13072-023-00485-8