Identifying altered developmental pathways in human globoid cell leukodystrophy iPSCs-derived NSCs using transcriptome profiling

BACKGROUND: Globoid cell leukodystrophy (GLD) is a devastating neurodegenerative disease characterized by widespread demyelination caused by galactocerebrosidase defects. Changes in GLD pathogenesis occurring at the molecular level have been poorly studied in human-derived neural cells. Patient-deri...

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Detalles Bibliográficos
Autores principales: Lv, Yafeng, Qin, Yu, Wang, Jing, Tian, Guoshuai, Wang, Wei, Cao, Chunyu, Zhang, Ye
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10116706/
https://www.ncbi.nlm.nih.gov/pubmed/37076788
http://dx.doi.org/10.1186/s12864-023-09285-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10116706/
https://www.ncbi.nlm.nih.gov/pubmed/37076788
http://dx.doi.org/10.1186/s12864-023-09285-6

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