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Targeting G-quadruplex motifs interferes with differentiation of adipose-derived mesenchymal stem cells

BACKGROUND: G-quadruplex (G4) motifs are nucleic acid secondary structures observed in mammalian genomes and transcriptomes able to regulate various cellular processes. Several small molecules have been developed so far to modulate G4 stability, frequently associated with anticancer activity. Howeve...

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Detalles Bibliográficos
Autores principales: Ambrosio, Maria Rosaria, Migliaccio, Teresa, Napolitano, Fabiana, Di Somma, Sarah, Maneli, Giovanni, Amato, Jussara, Pagano, Bruno, Randazzo, Antonio, Portella, Giuseppe, Formisano, Pietro, Malfitano, Anna Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10116735/
https://www.ncbi.nlm.nih.gov/pubmed/37076894
http://dx.doi.org/10.1186/s13287-023-03320-9