Silencing NTPDase3 activity rehabilitates the osteogenic commitment of post-menopausal stem cell bone progenitors

BACKGROUND: Endogenously released adenine and uracil nucleotides favour the osteogenic commitment of bone marrow-derived mesenchymal stromal cells (BM-MSCs) through the activation of ATP-sensitive P2X7 and UDP-sensitive P2Y(6) receptors. Yet, these nucleotides have their osteogenic potential comprom...

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Detalles Bibliográficos
Autores principales: Noronha-Matos, José Bernardo, Pinto-Cardoso, Rui, Bessa-Andrês, Catarina, Magalhães-Cardoso, Maria Teresa, Ferreirinha, Fátima, Costa, Maria Adelina, Marinhas, José, Freitas, Rolando, Lemos, Rui, Vilaça, Adélio, Oliveira, António, Pelletier, Julie, Sévigny, Jean, Correia-de-Sá, Paulo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10116749/
https://www.ncbi.nlm.nih.gov/pubmed/37076930
http://dx.doi.org/10.1186/s13287-023-03315-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10116749/
https://www.ncbi.nlm.nih.gov/pubmed/37076930
http://dx.doi.org/10.1186/s13287-023-03315-6

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