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Kernel-based genetic association analysis for microbiome phenotypes identifies host genetic drivers of beta-diversity

BACKGROUND: Understanding human genetic influences on the gut microbiota helps elucidate the mechanisms by which genetics may influence health outcomes. Typical microbiome genome-wide association studies (GWAS) marginally assess the association between individual genetic variants and individual micr...

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Detalles Bibliográficos
Autores principales: Liu, Hongjiao, Ling, Wodan, Hua, Xing, Moon, Jee-Young, Williams-Nguyen, Jessica S., Zhan, Xiang, Plantinga, Anna M., Zhao, Ni, Zhang, Angela, Knight, Rob, Qi, Qibin, Burk, Robert D., Kaplan, Robert C., Wu, Michael C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10116795/
https://www.ncbi.nlm.nih.gov/pubmed/37081571
http://dx.doi.org/10.1186/s40168-023-01530-0